No More Smokes

The brain before Chantix

The brain after Chantix
www.chantixguide.com

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CHANTIX CHEMICAL COMPOUND

http://www.rxlist.com/chantix-drug.htm
Chantix, varenicline, is a smoking cessation drug that contains no nicotine. It works in two ways. It attaches itself to the nicotine receptors in the brain, therefor, not allowing nicotine to reach these receptors. Chantix also activates these receptors to release smaller amounts of dopamine than nicotine. 44% of CHANTIX users had quit smoking during weeks 9 to 12 of treatment.
The dosage of Chantix is as follows:
Days 1 - 3: 0.5 mg once daily
Days 4 - 7: 0.5 mg twice daily
Day 8 - End of treatment: 1 mg twice daily
This dosage schedule is halved for severe renal patients.
The total course of the treatment should last 12 weeks.
Some of the commonly occurring side effects of Chantix are:
Nausea and vomiting
Headaches
Disturbed sleep and strange dreams
Gas
Food tasting different to usual (Dysgeusia)
Constipation, diarrhea and other digestive disturbances
Tiredness
Indigestion
Thirst
s common but more serious side effects of Chantix include:
Sensitivity to light and visual changes
Anemia
Pancreatitis
Hallucinations

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The only known contraindication of Chantix is age less than 18 years. However caution should be taken in renal and psychiatric patients.
How Chantix Works

"Stop Smoking Drug Approved on NHS"
http://news.bbc.co.uk/1/hi/health/6705667.stm

About the Chantix Study
1025 healthy smokers,aged 18 to 75, whom smoked atleast 10 cigarettes per day were given varenicline, bupropion, or a placebo for 12 weeks. 44% of the Chantix users had not smoked for 12 weeks and 21% had not smoked after one year. With bupropion 29% were still abstinent after 12 weeks and 16% after one year. Of the placebo users 17% were smoke free after 12 weeks and 8% after one year. Other such studies have yielded similar results.
JAMA.2006;296:47-71, 94-95

Figure 2 American Medical Association "Varenicline vs Bupropion and Placebo for Smoking Cessation"

LINKS:
www.chantix.com
http://www.rxlist.com/chantix-drug.htm
http://www.chantixguide.com/
https://online.epocrates.com/u/1034391/Chantix/